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Establishment and comprehensive characterization of a novel dark-reared zebrafish model for myopia studies

26 Jul 2024

Abstract excerpt

Myopia is predicted to impact approximately 5 billion people by 2050, necessitating mechanistic understanding of its development. Myopia results from dysregulated genetic mechanisms of emmetropization, caused by over-exposure to aberrant visual environments; however, these genetic mechanisms remain unclear. Recent human genome-wide association studies have identified a range of novel myopia-risk genes. To...

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PMID: 39067805
DOI: 10.1016/j.exer.2024.110009

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