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Article

LGR5 is Expressed by Ewing Sarcoma and Potentiates Wnt/β-Catenin Signaling

1 Jan 2013

Abstract excerpt

Ewing sarcoma (ES) is an aggressive bone and soft tissue tumor of putative stem cell origin that predominantly occurs in children and young adults. Although most patients with localized ES can be cured with intensive therapy, the clinical course is variable and up to one third of patients relapse following initial remission. Unfortunately, little is yet known about the biologic features that distinguish low-risk...

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PMID: 23596566
DOI: 10.3389/fonc.2013.00081

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