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Altered Expression of Diabetes-Related Genes in Alzheimer's Disease Brains: The Hisayama Study

17 Apr 2013

Abstract excerpt

Diabetes mellitus (DM) is considered to be a risk factor for dementia including Alzheimer's disease (AD). However, the molecular mechanism underlying this risk is not well understood. We examined gene expression profiles in postmortem human brains donated for the Hisayama study. Three-way analysis of variance of microarray data from frontal cortex, temporal cortex, and hippocampus was performed with the...

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PMID: 23595620
DOI: 10.1093/cercor/bht101

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