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Gene expression profile analysis of lymphocytes from Alzheimer??s patients

18 Feb 2005

Abstract excerpt

Since the function and metabolism of peripheral lymphocytes is known to be altered in Alzheimer's disease (AD), a pilot study was carried out to examine differences in gene expression profiles of these cells in 16 AD patients and aged control probands. Using a cDNA microarray representing 3200 distinct human genes, we identified 20 candidate genes whose expression is altered in AD lymphocytes compared with the...

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PMID: 15722950
DOI: 10.1097/00041444-200503000-00001

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