Article
Promoter-specific expression of the imprinted IGF2 gene in cattle (Bos taurus).
Biology of reproduction - 1 Dec 2005
Curchoe Carol, Zhang Shouquan, Bin Yanfang, Zhang Xiquan, Yang Lan, Feng Dingyuan, O'Neill Michael, Tian X Cindy
Abstract excerpt
The domestic cattle (Bos taurus) has been a good animal model for embryo biotechnologies, such as in vitro fertilization and nuclear transfer. However, animals produced from these technologies often suffer from large-calf syndrome, suggesting fetal growth disregulation. The product of the insulin-like growth factor 2 (IGF2) gene is one of the most important fetal mitogens known to date. A detailed analysis of...
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