Article
Allelic switching of the imprinted IGF2R gene in cloned bovine fetuses and calves.
Animal reproduction science - 1 Nov 2009
Suteevun-Phermthai T, Curchoe C L, Evans A C, Boland E, Rizos D, Fair T, Duffy P, Sung L Y, Du F, Chaubal S, Xu J, Wechayant T, Yang X, Lonergan P, Parnpai R, Tian X C
Abstract excerpt
Cloned animals often suffer from loss of development to term and abnormalities, typically classified under the umbrella term of Large Offspring Syndrome (LOS). Cattle are an interesting species to study because of the relatively greater success rate of nuclear transfer in this species compared with all species cloned to date. The imprinted insulin-like growth factor receptor (IGF2R; mannose-6-phosphate) gene was...
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