Article
Selection of antimalarial drug resistance after intermittent preventive treatment of infants and children (IPTi/c) in Senegal.
The American journal of tropical medicine and hygiene - 1 Jun 2013
Ndiaye Magatte, Tine Roger, Faye Babacar, Ndiaye Jean Louis, Lo Ami Colle, Sylla Khadime, Abiola Annie, Dieng Yémou, Ndiaye Daouda, Hallett Rachel, Gaye Oumar, Alifrangis Michael
Abstract excerpt
Our study investigated the possible impact of SP-IPT given to infants and children on the prevalence of SP-resistant haplotypes in the Plasmodium falciparum genes Pfdhfr and Pfdhps, comparing sites with and without IPTi/c. P. falciparum positive samples (N = 352) collected from children < 5 years were analyzed to determine the prevalence of SP resistance-related haplotypes by nested PCR followed by...
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