Lack of selection of antimalarial drug resistance markers after intermittent preventive treatment of schoolchildren (IPTsc) against malaria in northeastern Tanzania.

doi:10.1016/j.ijid.2024.107102

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Article

Lack of selection of antimalarial drug resistance markers after intermittent preventive treatment of schoolchildren (IPTsc) against malaria in northeastern Tanzania.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Sept 2024

Von Wowern Frederik, Makenga Geofrey, Wellmann Thomsen Sarah, Wellmann Thomsen Louise, Filtenborg Hocke Emma, Baraka Vito, Opot Benjamin H, Minja Daniel T R, Lusingu John P A, Van-Geertruyden Jean-Pierre, Hansson Helle, Alifrangis Michael

Abstract excerpt

OBJECTIVE: Intermittent Preventive Treatment of schoolchildren (IPTsc) is recommended by WHO as a strategy to protect against malaria; to explore whether IPTsc with dihydroartemisinin-piperaquine (DP) or artesunate-amodiaquine (ASAQ) cause a selection of molecular markers in Plasmodium falciparum genes associated with resistance in children in seven schools in Tanga region, Tanzania. METHODS: SNPs in P....

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PMID: 38876161
DOI: 10.1016/j.ijid.2024.107102

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