Article
Meta-analysis of the association between dopamine transporter genotype and response to methylphenidate treatment in ADHD.
The pharmacogenomics journal - 1 Feb 2014
Kambeitz J, Romanos M, Ettinger U
Abstract excerpt
Attention-deficit/hyperactivity disorder (ADHD) is a prevalent childhood-onset neuropsychiatric disorder. Treatment with methylphenidate, which blocks dopamine and noradrenaline transporters, is clinically efficacious in reducing the symptoms of ADHD. However, a considerable proportion of patients show no or only insufficient response to methylphenidate. Following a pharmacogenetic approach, a number of studies...
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