Article
Lung parenchyma surgery in autosomal dominant hyper-IgE syndrome.
Journal of clinical immunology - 1 Jul 2013
Freeman Alexandra F, Renner Ellen D, Henderson Carolyn, Langenbeck Anne, Olivier Kenneth N, Hsu Amy P, Hagl Beate, Boos Annette, Davis Joie, Marciano Beatriz E, Boris Lisa, Welch Pamela, Sawalle-Belohradsky Julie, Belohradsky Bernd H, Kwong King F, Holland Steven M
Abstract excerpt
PURPOSE: Autosomal dominant hyper-IgE syndrome (AD-HIES) due to heterozygous STAT3 mutation is a primary immunodeficiency characterized by eczema, elevated serum IgE, recurrent infections, and connective tissue and skeletal findings. Healing of pneumonias is often abnormal with formation of pneumatoceles and bronchiectasis. We aimed to explore whether healing after lung surgery is also aberrant. METHODS: We...
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