Article
[Association of CASP3 gene single nucleotide polymorphisms with Kawasaki disease in Chinese children patients].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Apr 2013
Peng Qian, Chen Chang-hui, Wu Qing, Li Bo, Liao Jing, Luo Cai-dan, Hu Xiao-ping, Zheng Zhi, Deng Yan, Zhang Yu
Abstract excerpt
OBJECTIVE: The minor allele T of rs113420705 (C/T) in caspase-3 gene (CASP3) has been found to significantly increase the risk of Kawasaki disease (KD) and complicate coronary artery lesions (CALs) in Japanese children. In this study, we have explored association of single nucleotide polymorphisms (SNPs) of CASP3 gene and clinic phenotypes of KD. METHODS: A total of 238 unrelated KD patients and 364 healthy...
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