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Article

A replication study for association of ITPKC and CASP3 two-locus analysis in IVIG unresponsiveness and coronary artery lesion in Kawasaki disease.

PloS one - 1 Jan 2013

Kuo Ho-Chang, Hsu Yu-Wen, Wu Chung-Min, Chen Shawn Hsiang-Yin, Hung Kuo-Sheng, Chang Wei-Pin, Yang Kuender D, Hsieh Kai-Sheng, Chen Wei-Chiao, Onouchi Yoshihiro, Chang Wei-Chiao

Abstract excerpt

Single-nucleotide polymorphisms (SNPs) in inositol 1,4,5-trisphosphate 3-kinase C (ITPKC, rs28493229) and caspase-3 (CASP3, rs113420705) are associated with susceptibility to KD in Japanese and Taiwanese populations. This study was conducted to investigate the involvement of these 2 SNPs in the risk for intravenous immunoglobulin (IVIG) resistance and coronary artery lesion (CAL) in Taiwanese population. A total...

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Source

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Identifiers

PMID: 23894522
DOI: 10.1371/journal.pone.0069685
PMCID: PMC3722201

Genes

CASP3
ITPKC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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