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Article

Regiospecific modifications of naringenin for astragalin production in Escherichia coli.

Biotechnology and bioengineering - 1 Sept 2013

Malla Sailesh, Pandey Ramesh Prasad, Kim Byung-Gee, Sohng Jae Kyung

Abstract excerpt

We report the production of astragalin (AST) from regiospecific modifications of naringenin (NRN) in Escherichia coli BL21(DE3). The exogenously supplied NRN was converted into dihydrokaempferol (DHK) and then kaempferol (KMF) in the presence of flavanone-3-hydroxylase (f3h) and flavonone synthase (fls1) from Arabidopsis thaliana, respectively. KMF was further modified to produce AST by 3-O-glucosylation...

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PMID: 23568509
DOI: 10.1002/bit.24919

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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