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Article

Oriented efficient biosynthesis of rare ginsenoside Rh2 from PPD by compiling UGT-Yjic mutant with sucrose synthase.

International journal of biological macromolecules - 1 Mar 2020

Ma Wang, Zhao Lu, Ma Yudi, Li Yuqiang, Qin Song, He Bingfang

Abstract excerpt

Ginsenoside Rh2 (3β-O-Glc-protopanaxadiol), a trace but an important pharmacological component of ginseng, has exhibited excellent medicinal potential. Many studies have found that the synthesis of Rh2 by UDP-glucosyltransferase (UGT) is an alternative production strategy. In this study, Yjic from B. subtilis 168 was found to synthesize ginsenoside F12 (3β,12β-Di-O-Glc-protopanaxadiol) and Rh2 at a ratio of 7:3....

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PMID: 31726169
DOI: 10.1016/j.ijbiomac.2019.09.208

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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