New components of Drosophila leg development identified through genome wide association studies.

Abstract excerpt

The adult Drosophila melanogaster body develops from imaginal discs, groups of cells set-aside during embryogenesis and expanded in number during larval stages. Specification and development of Drosophila imaginal discs have been studied for many years as models of morphogenesis. These studies are often based on mutations with large developmental effects, mutations that are often lethal in embryos when...

Topics

• Animals
• Cell Communication
• Drosophila Proteins
• Drosophila melanogaster
• Embryo, Nonmammalian
• Extremities