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Article

Knockdown of piRNA pathway proteins results in enhanced Semliki Forest virus production in mosquito cells

5 Apr 2013

Abstract excerpt

The exogenous siRNA pathway is important in restricting arbovirus infection in mosquitoes. Less is known about the role of the PIWI-interacting RNA pathway, or piRNA pathway, in antiviral responses. Viral piRNA-like molecules have recently been described following infection of mosquitoes and derived cell lines with several arboviruses. The piRNA pathway has thus been suggested to function as an additional small...

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PMID: 23559478
DOI: 10.1099/vir.0.053850-0

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