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Article

Characterization of the Zika virus induced small RNA response in Aedes aegypti cells

17 Oct 2017

Abstract excerpt

RNA interference (RNAi) controls arbovirus infections in mosquitoes. Two different RNAi pathways are involved in antiviral responses: the PIWI-interacting RNA (piRNA) and exogenous short interfering RNA (exo-siRNA) pathways, which are characterized by the production of virus-derived small RNAs of 25-29 and 21 nucleotides, respectively. The exo-siRNA pathway is considered to be the key mosquito antiviral response...

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PMID: 29040304
DOI: 10.1371/journal.pntd.0006010

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