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Article

Impact of NOD2 polymorphisms on infectious complications following chemotherapy in patients with acute myeloid leukaemia.

Annals of hematology - 1 Aug 2013

Yomade Olaposi, Spies-Weisshart Bärbel, Glaser Anita, Schnetzke Ulf, Hochhaus Andreas, Scholl Sebastian

Abstract excerpt

We sought to investigate the relationship between polymorphisms of the NOD2 gene and infectious complications following intensive induction chemotherapy in patients with acute myeloid leukaemia (AML). We hypothesised that single nucleotide polymorphisms (SNPs) of the NOD2 gene are associated with a higher rate of infections during the phase of severe neutropenia. In 131 AML patients receiving induction therapy,...

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Identifiers

PMID: 23558906
DOI: 10.1007/s00277-013-1734-0

Genes

NOD2

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