Article
New genes and new insights from old genes: update on Alzheimer disease.
Continuum (Minneapolis, Minn.) - 1 Apr 2013
Ringman John M, Coppola Giovanni
Abstract excerpt
PURPOSE OF REVIEW: This article discusses the current status of knowledge regarding the genetic basis of Alzheimer disease (AD) with a focus on clinically relevant aspects. RECENT FINDINGS: The genetic architecture of AD is complex, as it includes multiple susceptibility genes and likely nongenetic factors. Rare but highly penetrant autosomal dominant mutations explain a small minority of the cases but have...
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