Article
Association of a functional FAAH polymorphism with methamphetamine-induced symptoms and dependence in a Malaysian population.
Pharmacogenomics - 1 Apr 2013
Sim Maw Shin, Hatim Ahmad, Reynolds Gavin Paul, Mohamed Zahurin
Abstract excerpt
AIM: FAAH is a membrane enzyme that terminates the activity of a large class of endogenous signaling lipids. Recent studies suggest that the FAAH Pro129Thr polymorphism is a common mutation in the FAAH gene that is significantly associated with drug-addictive traits. This study investigated the association of the Pro129Thr polymorphism of the FAAH gene with methamphetamine dependence, methamphetamine-induced...
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