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Article

A new generation of modified live-attenuated avian influenza viruses using a two-strategy combination as potential vaccine candidates.

Journal of virology - 1 Sept 2007

Song Haichen, Nieto Gloria Ramirez, Perez Daniel R

Abstract excerpt

In light of the recurrent outbreaks of low pathogenic avian influenza (LPAI) and highly pathogenic avian influenza (HPAI), there is a pressing need for the development of vaccines that allow rapid mass vaccination. In this study, we introduced by reverse genetics temperature-sensitive mutations in the PB1 and PB2 genes of an avian influenza virus, A/Guinea Fowl/Hong Kong/WF10/99 (H9N2) (WF10). Further genetic...

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Identifiers

PMID: 17596317
DOI: 10.1128/JVI.00893-07
PMCID: PMC1951405

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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