Article
TALEN-based gene disruption in the dengue vector Aedes aegypti.
PloS one - 1 Jan 2013
Aryan Azadeh, Anderson Michelle A E, Myles Kevin M, Adelman Zach N
Abstract excerpt
In addition to its role as the primary vector for dengue viruses, Aedes aegypti has a long history as a genetic model organism for other bloodfeeding mosquitoes, due to its ease of colonization, maintenance and reproductive productivity. Though its genome has been sequenced, functional characterization of many Ae. aegypti genes, pathways and behaviors has been slow. TALE nucleases (TALENs) have been used with...
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