Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Silencing of end-joining repair for efficient site-specific gene insertion after TALEN/CRISPR mutagenesis in Aedes aegypti.

Proceedings of the National Academy of Sciences of the United States of America - 31 Mar 2015

Basu Sanjay, Aryan Azadeh, Overcash Justin M, Samuel Glady Hazitha, Anderson Michelle A E, Dahlem Timothy J, Myles Kevin M, Adelman Zach N

Abstract excerpt

Conventional control strategies for mosquito-borne pathogens such as malaria and dengue are now being complemented by the development of transgenic mosquito strains reprogrammed to generate beneficial phenotypes such as conditional sterility or pathogen resistance. The widespread success of site-specific nucleases such as transcription activator-like effector nucleases (TALENs) and clustered regularly interspaced...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aedes
Share to Clustered Regularly Interspaced Short Palindromic Repeats

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dimerization

Share to Gene Silencing

Share to Mutagenesis, Insertional

Share to RNA, Double-Stranded

Share to RNA Editing

Share to Transgenes

Source

Open in PubMed Open full text

Identifiers

PMID: 25775608
DOI: 10.1073/pnas.1502370112
PMCID: PMC4386333

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Silencing of end-joining repair for efficient site-specific gene insertion after TALEN/CRISPR mutagenesis in Aedes aegypti.PMID 25775608Read ↗

Genome engineering with CRISPR-Cas9 in the mosquito Aedes aegypti.Semantic proximity Read ↗

Genome-engineering with CRISPR-Cas9 in the mosquito <i>Aedes aegypti</i>Semantic proximity Read ↗

Germline Cas9 Expression Yields Highly Efficient Genome Engineering in a Major Worldwide Disease Vector, <i>Aedes aegypti</i>Semantic proximity Read ↗

Methods for TALEN Evaluation, Use, and Mutation Detection in the Mosquito Aedes aegypti.Semantic proximity Read ↗

A selectable, plasmid-based system to generate CRISPR/Cas9 gene edited and knock-in mosquito cell linesSemantic proximity Read ↗

Germline Cas9 expression yields highly efficient genome engineering in a major worldwide disease vector, Aedes aegyptiSemantic proximity Read ↗

TALEN-based gene disruption in the dengue vector Aedes aegypti.Semantic proximity Read ↗

Heritable CRISPR/Cas9-Mediated Genome Editing in the Yellow Fever Mosquito, Aedes aegyptiSemantic proximity Read ↗

Targeted genome editing in Aedes aegypti using TALENsSemantic proximity Read ↗

CRISPR mediated transactivation in the human disease vector Aedes aegyptiSemantic proximity Read ↗

Cre/lox-Recombinase-Mediated Cassette Exchange for Reversible Site-Specific Genomic Targeting of the Disease Vector, Aedes aegyptiSemantic proximity Read ↗

CRISPR Mediated Transactivation in the Human Disease Vector <i>Aedes aegypti</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.