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Article

Genome engineering with CRISPR-Cas9 in the mosquito Aedes aegypti.

Cell reports - 7 Apr 2015

Kistler Kathryn E, Vosshall Leslie B, Matthews Benjamin J

Abstract excerpt

The mosquito Aedes aegypti is a potent vector of the chikungunya, yellow fever, and dengue viruses, responsible for hundreds of millions of infections and over 50,000 human deaths per year. Mutagenesis in Ae. aegypti has been established with TALENs, ZFNs, and homing endonucleases, which require the engineering of DNA-binding protein domains to provide genomic target sequence specificity. Here, we describe the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25818303
DOI: 10.1016/j.celrep.2015.03.009
PMCID: PMC4394034

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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