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Article

Genetic interactions between neurofibromin and endothelin receptor B in mice.

PloS one - 1 Jan 2013

Deo Mugdha, Huang Jenny Li-Ying, Van Raamsdonk Catherine D

Abstract excerpt

When mutations in two different genes produce the same mutant phenotype, it suggests that the encoded proteins either interact with each other, or act in parallel to fulfill a similar purpose. Haploinsufficiency of Neurofibromin and over-expression of Endothelin 3 both cause increased numbers of melanocytes to populate the dermis during mouse development, and thus we are interested in how these two signaling...

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Identifiers

PMID: 23555837
DOI: 10.1371/journal.pone.0059931
PMCID: PMC3610757

Genes

GNAQ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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