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Article

Limits of [18F]-FLT PET as a biomarker of proliferation in oncology.

PloS one - 1 Jan 2013

McKinley Eliot T, Ayers Gregory D, Smith R Adam, Saleh Samir A, Zhao Ping, Washington Mary Kay, Coffey Robert J, Manning H Charles

Abstract excerpt

BACKGROUND: Non-invasive imaging biomarkers of cellular proliferation hold great promise for quantifying response to personalized medicine in oncology. An emerging approach to assess tumor proliferation utilizes the positron emission tomography (PET) tracer 3'-deoxy-3'[(18)F]-fluorothymidine, [(18)F]-FLT. Though several studies have associated serial changes in [(18)F]-FLT-PET with elements of therapeutic...

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PMID: 23554961
DOI: 10.1371/journal.pone.0058938
PMCID: PMC3598948

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PCNA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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