Article
Positron emission tomography imaging of cell proliferation in oncology.
Clinical oncology (Royal College of Radiologists (Great Britain)) - 1 May 2004
Kenny L M, Aboagye E O, Price P M
Abstract excerpt
Tumour-cell proliferation is a hallmark of the malignant phenotype. Positron emission tomography (PET) offers a unique method of imaging biological and biochemical changes in vivo. Radiolabelled thymidine and thymidine analogues are currently in development as PET tracers. By studying the uptake and kinetics of such compounds using PET, a measure of DNA synthesis and hence cell proliferation can be obtained....
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