Article
Assessment of simplified methods to measure 18F-FLT uptake changes in EGFR-mutated non-small cell lung cancer patients undergoing EGFR tyrosine kinase inhibitor treatment.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine - 1 Sept 2014
Frings Virginie, Yaqub Maqsood, Hoyng Lieke L, Golla Sandeep S V, Windhorst Albert D, Schuit Robert C, Lammertsma Adriaan A, Hoekstra Otto S, Smit Egbert F, Boellaard Ronald
Abstract excerpt
UNLABELLED: 3'-deoxy-3'-(18)F-fluorothymidine ((18)F-FLT) PET/CT provides a noninvasive assessment of proliferation and, as such, could be a valuable imaging biomarker in oncology. The aim of the present study was to assess the validity of simplified quantitative parameters of (18)F-FLT uptake in...
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