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Article

Tumor suppressor miR-375 regulates MYC expression via repression of CIP2A coding sequence through multiple miRNA-mRNA interactions.

Molecular biology of the cell - 1 Jun 2013

Jung Hyun Min, Patel Rushi S, Phillips Brittany L, Wang Hai, Cohen Donald M, Reinhold William C, Chang Lung-Ji, Yang Li-Jun, Chan Edward K L

Abstract excerpt

MicroRNAs (miRNAs) are small, noncoding RNAs involved in posttranscriptional regulation of protein-coding genes in various biological processes. In our preliminary miRNA microarray analysis, miR-375 was identified as the most underexpressed in human oral tumor versus controls. The purpose of the present study is to examine the function of miR-375 as a candidate tumor suppressor miRNA in oral cancer. Cancerous...

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Identifiers

PMID: 23552692
DOI: 10.1091/mbc.E12-12-0891
PMCID: PMC3667718

Genes

MYC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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