Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bmi-1-induced miR-27a and miR-155 promote tumor metastasis and chemoresistance by targeting RKIP in gastric cancer

24 Jun 2020

Abstract excerpt

BACKGROUND: We previously reported an inverse relationship between B cell-specific Moloney murine leukemia virus integration site 1 (Bmi-1) and Raf kinase inhibitory protein (RKIP), which is associated with the prognosis of gastric cancer (GC). In this study, we further explored the microRNA (miRNA) regulatory mechanism between Bmi-1 and RKIP. METHODS: Microarray analysis was first carried out to identify miRNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Myeloid Leukemia Treatments
Share to Melanoma and MAPK Pathways
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32580736
DOI: 10.1186/s12943-020-01229-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bmi-1-induced miR-27a and miR-155 promote tumor metastasis and chemoresistance by targeting RKIP in gastric cancerPMID 32580736Read ↗

RKIP inhibits the malignant phenotypes of gastric cancer cells.Semantic proximity Read ↗

Hematopoietic pre‐B cell leukemia transcription factor interacting protein is overexpressed in gastric cancer and promotes gastric cancer cell proliferation, migration, and invasionSemantic proximity Read ↗

Biological and therapeutic implications of RKIP in Gastrointestinal Stromal Tumor (GIST): an integrated transcriptomic and proteomic analysisSemantic proximity Read ↗

Raf Kinase Inhibitory Protein (RKIP) as a Metastasis Suppressor: Regulation of Signaling Networks in CancerSemantic proximity Read ↗

Long Non-Coding RNA GRIK1-AS1 Inhibits the Proliferation and Invasion of Gastric Cancer Cells by Regulating the miR-375/IFIT2 axisSemantic proximity Read ↗

MicroRNA-224 targets RKIP to control cell invasion and expression of metastasis genes in human breast cancer cellsSemantic proximity Read ↗

The m6A reader IGF2BP3 Facilitates Gastric Cancer Progression Through Activating EMT via Upregulating MYC mRNA StabilitySemantic proximity Read ↗

MicroRNA-559 restrains gastric cancer progression via activating AKT signaling pathway by targeting TRIM14Semantic proximity Read ↗

Pin1 inhibition potently suppresses gastric cancer growth and blocks PI3K/AKT and Wnt/β‐catenin oncogenic pathwaysSemantic proximity Read ↗

Deficiency of microRNA-628-5p promotes the progression of gastric cancer by upregulating PIN1Semantic proximity Read ↗

microRNA profiling of Iraqi patients with gastric cancerSemantic proximity Read ↗

PKMYT1 Promotes Gastric Cancer Cell Proliferation and Apoptosis ResistanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.