Article
Comparison of echocardiographic and cardiac magnetic resonance imaging in hypertrophic cardiomyopathy sarcomere mutation carriers without left ventricular hypertrophy.
Circulation. Cardiovascular genetics - 1 Jun 2013
Valente Anne Marie, Lakdawala Neal K, Powell Andrew J, Evans Sarah P, Cirino Allison L, Orav E John, MacRae Calum A, Colan Steven D, Ho Carolyn Y
Abstract excerpt
BACKGROUND: Left ventricular hypertrophy (LVH) typically manifests during or after adolescence in sarcomere mutation carriers at risk for developing hypertrophic cardiomyopathy. Guidelines recommend serial imaging of mutation carriers without LVH (G+/LVH-) to monitor for phenotypic evolution, but the optimal strategy is undefined. Compared with echocardiography (echo), cardiac MRI (CMR) offers improved...
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