Article
Specific phosphorylation of the PfRh2b invasion ligand of Plasmodium falciparum.
The Biochemical journal - 15 Jun 2013
Engelberg Klemens, Paul Aditya S, Prinz Boris, Kono Maya, Ching Wilhelm, Heincke Dorothee, Dobner Thomas, Spielmann Tobias, Duraisingh Manoj T, Gilberger Tim-Wolf
Abstract excerpt
Red blood cell invasion by the malaria parasite Plasmodium falciparum relies on a complex protein network that uses low and high affinity receptor-ligand interactions. Signal transduction through the action of specific kinases is a control mechanism for the orchestration of this process. In the present study we report on the phosphorylation of the CPD (cytoplasmic domain) of P. falciparum Rh2b (reticulocyte...
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