Article
Mapping and functional analysis of heterochromatin protein 1 phosphorylation in the malaria parasite Plasmodium falciparum.
Scientific reports - 13 Nov 2019
Bui Hai T N, Niederwieser Igor, Bird Megan J, Dai Weiwen, Brancucci Nicolas M B, Moes Suzette, Jenoe Paul, Lucet Isabelle S, Doerig Christian, Voss Till S
Abstract excerpt
Previous studies in model eukaryotes have demonstrated that phosphorylation of heterochromatin protein 1 (HP1) is important for dynamically regulating its various functions. However, in the malaria parasite Plasmodium falciparum both the function of HP1 phosphorylation and the identity of the protein kinases targeting HP1 are still elusive. In order to functionally analyze phosphorylation of P. falciparum HP1...
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