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Article

Pharmacogenetics of methylphenidate in childhood attention-deficit/hyperactivity disorder: long-term effects.

Scientific reports - 4 Sept 2017

Gomez-Sanchez Clara I, Carballo Juan J, Riveiro-Alvarez Rosa, Soto-Insuga Victor, Rodrigo Maria, Mahillo-Fernandez Ignacio, Abad-Santos Francisco, Dal-Ré Rafael, Ayuso Carmen

Abstract excerpt

Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in which a significant proportion of patients do not respond to treatment. The objective of this study was to examine the role of genetic risk variants in the response to treatment with methylphenidate (MPH). The effectiveness of MPH was evaluated based on variations in the CGI-S and CGAS scales over a 12-month treatment...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dopamine Plasma Membrane Transport Proteins

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Share to Receptors, Dopamine D4

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Source

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Identifiers

PMID: 28871191
DOI: 10.1038/s41598-017-10912-y
PMCID: PMC5583388

Genes

CGAS
ADGRL3
DRD2
DRD4
SNAP25

Provenance

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