Article
Buccals are likely to be a more informative surrogate tissue than blood for epigenome-wide association studies.
Epigenetics - 1 Apr 2013
Lowe Robert, Gemma Carolina, Beyan Huriya, Hawa Mohammed I, Bazeos Alexandra, Leslie R David, Montpetit Alexandre, Rakyan Vardhman K, Ramagopalan Sreeram V
Abstract excerpt
There is increasing evidence that interindividual epigenetic variation is an etiological factor in common human diseases. Such epigenetic variation could be genetic or non-genetic in origin, and epigenome-wide association studies (EWASs) are underway for a wide variety of diseases/phenotypes. However, performing an EWAS is associated with a range of issues not typically encountered in genome-wide association...
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