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Article

A correlation map of genome-wide DNA methylation patterns between paired human brain and buccal samples.

Clinical epigenetics - 1 Nov 2022

Sommerer Yasmine, Ohlei Olena, Dobricic Valerija, Oakley Derek H, Wesse Tanja, Sedghpour Sabet Sanaz, Demuth Ilja, Franke Andre, Hyman Bradley T, Lill Christina M, Bertram Lars

Abstract excerpt

Epigenome-wide association studies (EWAS) assessing the link between DNA methylation (DNAm) and phenotypes related to structural brain measures, cognitive function, and neurodegenerative diseases are becoming increasingly more popular. Due to the inaccessibility of brain tissue in humans, several studies use peripheral tissues such as blood, buccal swabs, and saliva as surrogates. To aid the functional...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36320053
DOI: 10.1186/s13148-022-01357-w
PMCID: PMC9628033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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