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Article

Development of an enzyme-linked immunosorbent assay (ELISA) to measure the level of tyrosine hydroxylase protein in brain tissue from Parkinson's disease models.

Journal of neuroscience methods - 15 May 2013

Fauss Donald, Motter Ruth, Dofiles Lilibeth, Rodrigues Maria Armanda Viana, You Monica, Diep Linnea, Yang Yangli, Seto Pui, Tanaka Kevin, Baker Jeanne, Bergeron Marcelle

Abstract excerpt

Tyrosine hydroxylase (TH) catalyses the rate-limiting step in the biosynthesis of catecholamines. TH expression is regulated in a tissue-specific manner during neuronal development and differentiation. Because of its key regulatory role in central and peripheral catecholamine synthesis, TH is associated with the pathogenesis of several neurological and psychiatric diseases, including Parkinson's disease,...

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PMID: 23537934
DOI: 10.1016/j.jneumeth.2013.03.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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