Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hepatocellular carcinoma as extracolonic manifestation of Lynch syndrome indicatesSEC63as potential target gene in hepatocarcinogenesis

5 Feb 2013

Abstract excerpt

OBJECTIVE: Lynch syndrome is a cancer predisposition syndrome caused by germline mutations in DNA mismatch repair (MMR) genes with microsatellite instability (MSI) as its molecular hallmark. Hepatocellular carcinoma (HCC) has not been considered part of the tumor spectrum. The aim was to provide a detailed molecular characterization of an HCC associated with Lynch Syndrome (Muir-Torre variant). MATERIALS AND...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Connective tissue disorders research
Share to Ferroptosis and cancer prognosis
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23537056
DOI: 10.3109/00365521.2012.752030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Hepatocellular carcinoma as extracolonic manifestation of Lynch syndrome indicatesSEC63as potential target gene in hepatocarcinogenesisPMID 23537056Read ↗

Genomic and transcriptomic analyses of chemical hepatocarcinogenesis aggravated by oncoprotein lossSemantic proximity Read ↗

Hepatocellular carcinoma as a complex polygenic disease. Interpretive analysis of recent developments on genetic predisposition.Semantic proximity Read ↗

3‐Mercaptopyruvate sulfurtransferase represses tumour progression and predicts prognosis in hepatocellular carcinomaSemantic proximity Read ↗

Genetic instability occurs sooner than expected: promotion, progression and clonality during hepatocarcinogenesis in the rat.Semantic proximity Read ↗

Tumor spectrum in lynch syndrome, DNA mismatch repair system and endogenous carcinogens.Semantic proximity Read ↗

Comparison of liver oncogenic potential among human RAS isoforms.Semantic proximity Read ↗

Activation of SRY accounts for male-specific hepatocarcinogenesis: Implication in gender disparity of hepatocellular carcinoma.Semantic proximity Read ↗

RNA Sequencing Reveals Divergent Transcriptome Changes in SBP2 and SECISBP2L Depleted Cell LinesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.