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Article

Dual role for Hox genes and Hox co-factors in conferring leg motoneuron survival and identity in Drosophila.

Development (Cambridge, England) - 1 May 2013

Baek Myungin, Enriquez Jonathan, Mann Richard S

Abstract excerpt

Adult Drosophila walk using six multi-jointed legs, each controlled by ∼50 leg motoneurons (MNs). Although MNs have stereotyped morphologies, little is known about how they are specified. Here, we describe the function of Hox genes and homothorax (hth), which encodes a Hox co-factor, in Drosophila leg MN development. Removing either Hox or Hth function from a single neuroblast (NB) lineage results in MN...

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Identifiers

PMID: 23536569
DOI: 10.1242/dev.090902
PMCID: PMC3631975

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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