Joint morphology in the insect leg: evolutionary history inferred from Notch loss-of-function phenotypes in Drosophila.

Abstract excerpt

Joints permit efficient locomotion, especially among animals with a rigid skeleton. Joint morphologies vary in the body of individual animals, and the shapes of homologous joints often differ across species. The diverse locomotive behaviors of animals are based, in part, on the developmental and evolutionary history of joint morphogenesis. We showed previously that strictly coordinated cell-differentiation and...

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