Article
huckebein specifies aspects of CNS precursor identity required for motoneuron axon pathfinding.
Neuron - 1 Nov 1995
Chu-LaGraff Q, Schmid A, Leidel J, Brönner G, Jäckle H, Doe C Q
Abstract excerpt
huckebein encodes a putative zinc finger protein expressed in a subset of Drosophila CNS precursors, including the NB 4-2/GMC 4-2a/RP2 cell lineage. In huckebein mutant embryos, GMC 4-2a does not express the cell fate marker EVEN-SKIPPED; conversely, huckebein overexpression produces a duplicate EVEN-SKIPPED-positive GMC 4-2a. We use Dil to trace the entire NB 4-2 lineage in wild-type and huckebein mutant...
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