huckebein specifies aspects of CNS precursor identity required for motoneuron axon pathfinding.

doi:10.1016/0896-6273(95)90093-4

Back to search

Article

huckebein specifies aspects of CNS precursor identity required for motoneuron axon pathfinding.

Neuron - 1 Nov 1995

Chu-LaGraff Q, Schmid A, Leidel J, Brönner G, Jäckle H, Doe C Q

Abstract excerpt

huckebein encodes a putative zinc finger protein expressed in a subset of Drosophila CNS precursors, including the NB 4-2/GMC 4-2a/RP2 cell lineage. In huckebein mutant embryos, GMC 4-2a does not express the cell fate marker EVEN-SKIPPED; conversely, huckebein overexpression produces a duplicate...

Topics

Animals
Axons
Cell Differentiation
Central Nervous System
DNA-Binding Proteins
Drosophila
Drosophila Proteins
Gene Expression
Motor Neurons
Mutation
Pedigree
Stem Cells
Zinc Fingers

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.