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Article

The Caenorhabditis elegans gene ham-2 links Hox patterning to migration of the HSN motor neuron.

Genes & development - 15 Feb 1999

Baum P D, Guenther C, Frank C A, Pham B V, Garriga G

Abstract excerpt

The Caenorhabditis elegans HSN motor neurons permit genetic analysis of neuronal development at single-cell resolution. The egl-5 Hox gene, which patterns the posterior of the embryo, is required for both early (embryonic) and late (larval) development of the HSN. Here we show that ham-2 encodes a zinc finger protein that acts downstream of egl-5 to direct HSN cell migration, an early differentiation event. We...

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Identifiers

PMID: 10049362
DOI: 10.1101/gad.13.4.472
PMCID: PMC316472

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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