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Article

Mutations at the monomer-monomer interface away from the active site of influenza B virus neuraminidase reduces susceptibility to neuraminidase inhibitor drugs.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Oct 2013

Fujisaki Seiichiro, Imai Masaki, Takashita Emi, Taniwaki Tae, Xu Hong, Kishida Noriko, Yokoyama Masaru, Sato Hironori, Tashiro Masato, Odagiri Takato

Abstract excerpt

Amino acid changes in or near the active site of neuraminidase (NA) in influenza viruses reduce the susceptibility to NA inhibitor drugs. Here, we report the recovery of three influenza B viruses with reduced susceptibilities to NA inhibitors from human patients with no history of antiviral drug...

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Identifiers

PMID: 23529501
DOI: 10.1007/s10156-013-0589-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-23529501-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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