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Article

The clinicopathologic significance of p53 and BAF-250a (ARID1A) expression in clear cell carcinoma of the endometrium.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 2013

Fadare Oluwole, Gwin Katja, Desouki Mohamed M, Crispens Marta A, Jones Howard W, Khabele Dineo, Liang Sharon X, Zheng Wenxin, Mohammed Khaled, Hecht Jonathan L, Parkash Vinita

Abstract excerpt

TP53 mutation (and associated p53 protein overexpression) is probably a negative prognostic marker in endometrial cancers, but its relevance in the rarer histologic subtypes, including clear cell carcinomas, has not been delineated. Preclinical studies suggest functional interactions between p53 and the BAF250a protein, the product of a tumor suppressor gene ARID1A (adenine-thymine (AT)-rich interactive domain...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23524907
DOI: 10.1038/modpathol.2013.35
PMCID: PMC3886836

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