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Article

Novel association of SNP rs2297828 in PRDM16 gene with predisposition to type 2 diabetes.

Gene - 15 Jan 2023

Zhang Hongmei, Guan Qiuyue, Wang Ruyi, Yang Shanshan, Yu Xiaoqian, Cui Daxin, Su Zhiguang

Abstract excerpt

OBJECTIVES: Transcriptional regulator PRD1-BF-1-RIZ1 homology (PR) domain containing protein-16 (PRDM16) has a fundamental function in maintaining energy homeostasis and regulating glucose and lipid metabolism, which are responsible for the development of type 2 diabetes (T2D). However, the impact of genetic variation of PRDM16 gene on T2D risk remains to be investigated. Thus, we evaluated the possible...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 36174906
DOI: 10.1016/j.gene.2022.146916

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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