Article
Sequence variants in the bovine PRDM16 gene associated with body weight in Chinese cattle breeds.
Genetics and molecular research : GMR - 22 Mar 2012
Wang J, Wang C, Tian R, Huang Y-Z, Lai X-S, Lan X-Y, Wang J-Q, Chen H
Abstract excerpt
As a zinc-finger protein, PR domain containing 16 (PRDM16) controls brown fat determination by stimulating brown fat cell production while suppressing the expression of genes for production of white fat cells; mutations in this domain are associated with myelodysplastic syndrome and leukemogenesis. In our study, polymorphisms in exons 2, 3, 4, 5, 7, 8, and 9 of the PRDM16 gene were detected by PCR-SSCP, DNA...
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