Article
Two novel SNPs in the coding region of the bovine PRDM16 gene and its associations with growth traits.
Molecular biology reports - 1 Jan 2010
Wang J, Li Z J, Lan X Y, Hua L S, Huai Y T, Huang Y Z, Ma L, Zhao M, Jing Y J, Chen H, Wang J Q
Abstract excerpt
As a zinc-finger protein, PR domain containing 16 (PRDM16) controls brown fat determination by stimulating brown fat-selective genes expression while suppressing the expression of genes selective for white fat cells, whose mutations were associated with myelodysplastic syndrome (MDS) and leukemogenesis in human and murine model of leukemia. To date, no polymorphisms of PRDM16 gene in bovine had been reported....
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