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Article

Peripheral motor axons of SOD1(G127X) mutant mice are susceptible to activity-dependent degeneration.

Neuroscience - 25 Jun 2013

Alvarez S, Calin A, Graffmo K S, Moldovan M, Krarup C

Abstract excerpt

Motor neuron disorders may be associated with mitochondrial dysfunction, and repetitive electrical impulse conduction during energy restriction has been found to cause neuronal degeneration. The aim of this study was to investigate the vulnerability of motor axons of a presymptomatic late-onset, fast-progression SOD1(G127X) mouse model of amyotrophic lateral sclerosis to long-lasting, high-frequency repetitive...

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Identifiers

PMID: 23523994
DOI: 10.1016/j.neuroscience.2013.03.017

Genes

SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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