Sodium Channels, Mitochondria, and Axonal Degeneration in Peripheral Neuropathy.

Abstract excerpt

Peripheral neuropathy results from damage to peripheral nerves and is often accompanied by pain in affected limbs. Treatment represents an unmet medical need and a thorough understanding of the mechanisms underlying axonal injury is needed. Longer nerve fibers tend to degenerate first (length-dependence), and patients carrying pathogenic mutations throughout life usually become symptomatic in mid- or late-life...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Axons
• Share to Mitochondria
• Share to Mutation