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High Dietary Fat Consumption Impairs Axonal Mitochondrial FunctionIn Vivo

30 Mar 2021

Abstract excerpt

Peripheral neuropathy (PN) is the most common complication of prediabetes and diabetes. PN causes severe morbidity for Type 2 diabetes (T2D) and prediabetes patients, including limb pain followed by numbness resulting from peripheral nerve damage. PN in T2D and prediabetes is associated with dyslipidemia and elevated circulating lipids; however, the molecular mechanisms underlying PN development in prediabetes...

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PMID: 33785643
DOI: 10.1523/jneurosci.1852-20.2021

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